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Understanding Glomerulonephritis: What It Is and How It Affects Your Kidneys

Medically Approved by Dr. Seema

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glomerulonephritisEven though it may be unfamiliar to you, glomerulonephritis has to do with a sertain type of inflammation of the kidneys which is rather severe and needs urgent attention. A kidney disease, glomerulonephritis can show mild and short-lived symptoms or can be serious and chronic. In the absence of accurate diagnosis and treatment, the patient is likely to suffer from kidney failure. In this blog, we will address the questions: What is glomerulonephritis? What causes the disease? What some of the common symptoms are? What type of glomerulonephritis are there? Lastly, we will provide chronically why the illness needs to be diagnosed early and what are the ways to tackle it effectively.

What is Glomerulonephritis?

Glomerulonephritis is a type of kidney disease that arises due to inflammation of glomeruli. The glomeruli are the parts of the Kidney which has the role of filtering, Glomeruli use the urinary system to remove waste, extra fluids, and certain ions, when the structures begin to swell, they can no longer filter blood properly. If that happens, damage to kidneys is unavoidable.

The causes also range from infections, autoimmune diseases, and even hereditary disorders, inflammation can result in an infection having multiple possible causes and may range from something sudden (acute) to something gradual (chronic). Children and adults can be afflicted by these conditions without any type of treatment, further complications can be developed such as heart failure, edema hypertension and heart failure.

How and why do these brings about glomerulonephritis eithitis and how does it differ from these other kidney infections? Glomerulonephritis Eithitis Inflammation causes:

A blend of both glomeruli stretching glomeruli a single capillary tuft along with early stages of chronic or excess inflammation led to the disorder. Alongside inflammation there are some factors which result in inflammation of the glomeruli, some are.

  1. Infections: Certain infections for example pus producing infections often lead to streptococcus infections towards strep throat and are pretty common. Viral infections alongside some other diseases also undertake this condition.
  2. Autoimmune diseases: Some disorders that are more autoimmune such as lupus or certain viral infections like the HIV contribute towards inflammation.
  3. Genetic disorders: Other types seem to be more and more passed down, for instance Alport syndrome which tend to run in families can be diagnosed later in life when the kidney disease gradually leads to kidney failure.
  4. Vasculitis: This is inflammation of specific blood vessels that may lead to kidney injury with accompanying glomerulonephritis. Common types of vasculitis that affect the kidneys include polyangiitis granulomatosis and microscopic polyangiitis.
  5. Causes: Causes might include kidney disease due to diabetes, poorly controlled hypertension, or previous episodes of nephrolithiasis. These increase the likelihood of developing glomerulonephritis.

Glomerulonephritis Symptoms The symptoms of glomerulonephritis depend on the degree of severity of the disease as well as the acute or chronic features. Some individuals can appear strangely unwell while others may appear to have advanced kidney disease.

Some of the symptoms associated with glomerulonephritis

  1. During slowdown of kidney function – body parts start to swell more than usual. This condition is called enema. This is one of the most characteristic symptoms that patients can notice and it affects, the face and sometimes the arms, ankles, and feet. This happens because the kidneys are not working correctly which causes the fluids to build up.
  2. Foamy Urine – If your urine has some foam, it may be from protein supplements taken at some point. In worse condition, it could suggest glomerulonephritis. In either case, it is best to get a consult. As the glomeruli get damaged, they begin to spill out protein, therefore making excess protein in urine.
  3. High Blood Pressure – Glomerulonephritis tends to perform Kirk’s law to the kidney inflammation too. This also would increase hypertension, which in turn would damage the kidney. If you have persistent high blood pressure together with pain on the kidney region, that is more advanced case like renal failure.
  4. Blood Urine (Hematuria) – Foamy urine mixed with blood and pink or cola color urine is a good sign of glomerulonephritis. is where the capillaries that course with the glomeruli are damaged, therefore starting to leak red blood cells.
  5. Fatigue – Benign the problem, leaves too much toxicity and waste in the blood, which isn’t good for normal functioning of the body. That caused extreme tiredness and fatigue, in some scenarios tiredness.
  6. Decreased Urine Output – As already mentioned and simplified, less urine being produced could mean one is undergoing kidney ablation or is in the later stages of kidney failure.

In the event that any changes to your health, such as unexplained swelling or blood in urine, has been noticed, it is time to get help from a medical expert without delay.

Categories of Glomerulonephritis: Exploring the Differences 

There are different types of glomerulonephritis, each of which has several distinguishing characteristics, causes, and management approaches. Familiarity with these types may be useful in deciding the appropriate actions that healthcare staff need to take.

  1. Acute Glomerulonephritis: This one tends to manifest rather quickly. If you had a “strep throat,” this type may come with it. In the more severe cases, doctors have treatment plans in hand that can ease many of the side effects. Some people, without help, might cross over to chronic glomerulonephritis.
  2. Chronic Glomerulonephritis: This one forms slowly, typically over several years. This means that if diagnosed early on, it would be more manageable. For the final stages of this illness, dialysis or kidney removal accompanied by a transplant would be necessary.
  3. IgA Nephropathy: This is one of the most prevalent forms of glomerulonephritis. It results from an excess build up of immunoglobulin A (IgA) in the kidneys, causing them to become inflamed. This syndrome is typically slow to progress, often parallel with the gradual decrease in kidney function.
  4. This syndrome is characterized by a thickening of the glomeruli membrane. It often progresses to nephrotic syndrome and its associated symptoms which include significant protein excretion > 3.5 grams a day.
  5. This type of glomerulonephritis is one of the most severe and progresses continuously worse with a high risk of renal failure in weeks to months. It often requires immediate medical care attention.

Long-Term Perspective On Kidney Damage: Chronic Glomerulonephritis

Chronic glomerulonephritis is a fairly common term used for a long standing form of kidney disease. Along with gradual destruction of kidney tissues, it can result into kidney tissues failing completely. With time, as the kidney glomeruli gets scarring, they are unable to optimally filter the wastes from the blood. Eventually, chronic glomerulonephritis will result into end stage kidney disease (ESKD) when kidneys cease to function and the patient has to depend on dialysis or transplantation.

 

The chronic stages of glomerulonephritis continue being symptom free but non symptomatic does not mean that the health does not deteriorate over time. Glomerulonephritis PPT (progression, prognosis, and treatment) helps understand by expanding on the myriad of impacts this condition causes on patient’s life and health, giving insight into this disorder and steps needed to take.

 

The Importance of Kidney Function Tests

Combining a physical examination with urinalysis, blood work, and imaging techniques is considered the most effective method to accurately diagnose an individual as a patient with chronic glomerulonephritis. The most commonly use diagnostic exam consists of:

  1. Urinalysis: In this instance, urine is tested for blood, proteins or any other abnormal substances that indicate the presence of glomerulonephritis.
  2. Blood Tests: The examination of the concentration of a serum creatinine and the blood urea nitrogen (BUN) measure waste in the blood is one method of estimation of creatinine clearance or glomerular filtration rate.
  3. Kidney Biopsy: Occasionally a biopsy of the kidney will be done and the specimen of the kidney tissue will be examined microscopically. This determines the type of glomerulonephritis and what treatment may be possible to undertake.
  4. Imaging Tests: With ultrasound or CT scan the abnormal structural alterations of the kidneys and associated diseases may be evaluated, as well as the size of the kidneys themselves.

 

World Kidney Day, also known as Kidney Day, snoozes an alarm clock to remind the public to learn more about their kidneys. People around the world that maintain a healthy living in turn avoid becoming victims of ill kidney health and believe this should be further promoted, along with the increase the necessity of diagnosis and treatment of kidney diseases such Glomerulonephritis and other forms. Regular testing, particularly for those at risk, can lower the damage done and improve all-around outcomes.

Kidney filtration can be affected very much by use and waste. Attention and treatment of acute or chronic glomerulonephritis should always correct at the stage of diagnosis. Keeping track of possible causes and symptoms, as well as different types of lesions, helps manage the condition before it becomes uncontrollable. If the concerning issue rests on the state of kidney health and suspicion of having glomerulonephritis, a kidney function test should be undertaken as soon as possible to allow timely intervention and management of any underlying pathology.

 

Make an effort to raise awareness on kidney health issues and check with your doctor regularly to enable effective protection of your kidneys this World Kidney Day.

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