TOXOPLASMA ANTIBODIES PANEL IgG & IgM, SERUM Test in Agra

  • recommend icon

    Test Recommended For:

    Male, Female

  • Report Frequency :

    Daily

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  • parameter icon

    Parameters :

    3

Special Instruction :
No special preparation required

Overview

Toxoplasmosis is a disease caused by the parasite Toxoplasma gondii. You get infected with the parasite usually by eating undercooked contaminated meat or by exposure from infected stool of cats or mother to child transmission during pregnancy. Symptoms are similar to that of Flu in adults. Children born to infected mothers can be stillborn or can have serious problems such as eye infections & fits. If you have Toxoplasma IgG antibodies in your blood, it is suggestive of past infection. If you have Toxoplasma IgM antibodies in your blood, it is suggestive of recent infection.

Parameters

Doctor Information

Code

Pre-test Information

No special preparation required

Code

Report Delivery

Daily

Code

Code

Z197

Category

Category

Abortions, Infections

Stability Room

Stability Room

2 hrs

Stability Refrigerated

Stability Refrigerated

4 days

Stability Frozen

Stability Frozen

4 weeks

Method

Method

CMIA

Specimen

Usage

Toxoplasma gondii is an obligate intracellular parasite capable of infecting a wide variety of intermediate hosts including man. Toxoplasmosis is acquired by humans through ingestion of food or water contaminated with cat feces or through eating undercooked meat containing viable oocysts. Vertical transmission of the parasite through the placenta can also occur, leading to congenital toxoplasmosis. Infection in man is usually asymptomatic. Following primary infection, Toxoplasma gondii can remain latent for the life of the host; the risk for reactivation is highest among immunosuppressed individuals. The most common symptomatic presentation in man is lymphadenopathy, encephalitis, myocarditis and pneumonitis. Demonstration of Toxoplasma IgG in the serum of person with eye lesion helps in diagnosing Ocular toxoplasmosis. In addition, antibody levels and demonstration of parasite DNA in aqueous humor confirms the diagnosis of Ocular toxoplasmosis. Persistent or increasing IgG antibody levels in the infant compared with the mother and/or positive result of Toxoplasma specific IgM or IgA are diagnostic of Congenital toxoplasmosis. Demonstration of Toxoplasma specific IgG in CSF can help confirm the diagnosis of Congenital toxoplasmosis when the results are compared to serum Toxoplasma specific IgG levels. Congenital toxoplasmosis occurs when a woman passes the infection to her fetus after acquiring a primary infection during pregnancy or more rarely, when a pregnant woman is immunocompromised and a previously acquired infection is reactivated with an overall transmission rate varying between 30% to 50 % depending on the stage of pregnancy. Demonstrating Toxoplasmic specific IgM & IgA antibodies in fetal serum or isolating Toxoplasma from fetal leucocytes is a definitive diagnosis of fetal infection.

Specimen

Specimen

2 mL (1 mL min.) Serum from 1 SST. Ship refrigerated or frozen.

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