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- MEDULLARY THYROID CARCINOMA, MUTATION DETECTION

MEDULLARY THYROID CARCINOMA, MUTATION DETECTION Test in Agartala

Test Recommended For:
Male

Report Frequency :
Sample Daily by 11 am; Report 10 Working days

Parameters :
1


Parameters :
1
- ₹ 17600
- 50+

Quality Checks & Processes On Every Sample
15+Quality Indicator Monitored On Daily Basis
Overview
Medullary thyroid carcinoma (MTC) is a type of thyroid cancer that is uncommon but more aggressive. It arises from special cells in the thyroid gland called C cells that secrete a hormone called Calcitonin. This type of cancer is seen to run in families & shows a typical genetic mutation. Patients usually have no symptoms but some may develop a lump in the neck. Some patients have no family history of MTC. These patients are usually older & develop more extensive disease. This assay detects the gene mutation.
Parameters
Doctor Information

Pre-test Information
Physician prescription is mandatory.

Report Delivery
Sample Daily by 11 am; Report 10 Working days

Code
OS161

Category
N/A

Stability Room
NA

Stability Refrigerated
1 week

Stability Frozen
NA

Method
PCR

Usage
Mutations (DNA changes) in the RET proto-oncogene, located on chromosome 10, lead to the expression of a mutated receptor tyrosine kinase protein, termed RET (REarranged during Transfection). RET is involved in the regulation of cell growth & development and its germline mutation is responsible for nearly all cases of Hereditary or Familial Medullary thyroid carcinoma. Its germline mutation may also be responsible for the development of Hyperparathyroidism and Pheochromocytoma.

Specimen
4 mL (2 mL min.) Whole blood in 1 Lavender top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. Physician prescription is mandatory.
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