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Home > Breast Cancer

  • Overview
  • Symptoms
  • Risk Factor
  • Diagnosis
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Overview

Breast cancer occurs when some breast cells begin to grow abnormally. These cells divide more rapidly than healthy cells do and continue to accumulate, forming a lump or mass. Cells may spread (metastasize) through your breast to your lymph or to other parts. Breast cancer can occur in both men and women, but it's far more common in women. Breast cancer survival rates have increased, and the number of deaths associated with this disease is steadily declining, largely due to factors such as:

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    Earlier detection
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    New personalized approach to treatment
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    Better understanding of the disease

Incidence & Epidemiology

Overall 1 in 28 women is likely to develop breast cancer during her lifetime.

Symptoms

Breast lump

A Breast lump of thickening that feels different from the surrounding tissue

Change in the size

Change in the size, shape or appearance of the breast

Changes to the skin

Changes to the skin over the breast, such as dimpling

Peeling

Peeling, scaling, crusting or flaking of the pigmented are surrounding the nipple (areola) or breast skin

Redness or pitting

Redness or pitting of the skin over the breast, like the skin of an orange

inverted nipple

A newly inverted nipple

Type

Invasive breast cancers

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    Invasive carcinoma of no special type
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    Tubular carcinoma
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    Medullary carcinoma
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    Invasive lobular carcinoma
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    Invasive micropapillary carcinoma
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    Metaplastic carcinoma
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    Mucinous carcinoma
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    Invasive papillary carcinoma
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    Adenoid cystic carcinoma

Invasive breast cancers

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    DCIS (Ductal carcinoma in situ)
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    ALH (Atypical lobular hyperplasia
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    LCIS (Lobular carcinoma in situ)
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    ADH (Atypical ductal hyperplasia

Risk Factor

Women taking

Women taking hormone medications

Beginning menopause

Beginning menopause at an older age

breast cancers

5 to 10 percent of breast cancers are linked to gene mutations.

Drinking alcohol

Drinking alcohol increases the risk of breast cancer.

Women never

Women never been pregant have a greater risk.

Women having

Women having childbirth after age 30.

Beginning your period

Beginning your period at a younger age before 12.

Being obese increases

Being obese increases your risk of breast cancer.

Exposure to radiation

Exposure to radiation increases risk of breast cancer.

increase cancer risk

That increase cancer risk: Gene mutations BRCA1 & BRCA2.

Personal history

Personal history of breast conditions.

Risk of breast cancer

Risk of breast cancer increases as you age.

develop breast cancer

Women are much more likely than men are to develop breast cancer.

Inherited breast cancer

Bone-Marrow-Tests

About 5 to 10 percent of breast cancers are linked to gene mutations passed through generations of a family. The most well-known are breast cancer gene 1 (BRCA1) and breast cancer gene 2 (BRCA2), both...

PARP

PARP (poly-ADP ribose polymerase) is a protein found in our cells, helps damaged cells to repair themselves. In a cancer patient, PARP inhibitor stops PARP from doing its repair work and so the cancer...

Dr Lal Pathlabs Videos

Dr Himangshu Mazumdar - Dr Lal PathLabs

Dr Nimmi Kansal - Dr Lal PathLabs

Diagnosis

Risk Factor

Risk Factor

Breast examination

Breast examination

Mammogram

Mammogram

Breast ultra sound

Breast ultra sound

Biopsy

Biopsy

Cervical-Cancer

Breast MRI

Core needle biopsy

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    A core needle biopsy uses a long, hollow tube to extract a core of tissue.
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    A biopsy is the only definitive way to make a diagnosis of breast cancer. During a biopsy, your doctor uses a specialized needle device guided by X-ray or another imaging test to extract a core of tissue from the suspicious area. Often, a small metal marker is left at the site within your breast so the area can be easily identified on future imaging tests.
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    Biopsy samples are sent to a laboratory for analysis where experts determine whether the cells are cancerous.

Staging breast cancer

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    Once your doctor has diagnosed your breast cancer, he or she works to establish the extent (stage) of your cancer.
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    Your cancer's stage helps determine your prognosis and the best treatment options.
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    Complete information about your cancer's stage may not be available until after you undergo breast cancer surgery.

Tests for Breast Cancer

Breast cancer stages range from 0 to IV with 0 indicating cancer that is noninvasive or contained within the milk ducts. Stage IV breast cancer, also called metastatic breast cancer, indicates cancer that has spread to other areas of the body.Breast cancer staging also takes into account your cancer's grade; the presence of tumor markers, such as receptors for estrogen, progesterone and HER2; and proliferation factors.

  • Clinical Work up
  • Department

Additional relevant tests

ONCOPRO HEREDITARY CANCER RISK PANEL

BRCA1 & BRCA2 MUTATION DRUG PROFILING PANEL

CANCER 50 GENE PANEL, NGS

Diagnostic work up

FISH: HER2 (ERBB2) AMPLIFICATION

CANCER BREAST COMPREHENSIVE PANEL

COMPLETE BLOOD COUNT; CBC

CYTOLOGY FINE NEEDLE ASPIRATION; FNAC

HISTOPATHOLOGY BIOPSY: SMALL SPECIMEN

HISTOPATHOLOGY BIOPSY: LARGE COMPLEX / CANCER SPECIMEN

IMMUNOHISTOCHEMISTRY: HER-2 / ERBB2 BREAST

BREAST CANCER PANEL 1

IMMUNOHISTOCHEMISTRY: BREAST CANCER PANEL 2

Follow up

BREAST METASTATIC MARKER

CA 27.29 & CA 15.3; BREAST CANCER MARKERS PANEL

BREAST MONITOR PANEL

CA 15.3; BREAST CANCER MARKER

CA 27.29; BREAST CANCER MARKER

ONCOPRO LIQUID BIOPSY

Prognostic work up

IMMUNOHISTOCHEMISTRY: HER-2 / ERBB2 BREAST

BREAST CANCER PANEL 1

IMMUNOHISTOCHEMISTRY: BREAST CANCER PANEL 2

CAN ASSIST BREAST

FISH: HER2 (ERBB2) AMPLIFICATION

CANCER BREAST COMPREHENSIVE PANEL

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