OXCARBAZEPINE METABOLITE

Oxcarbazepine (OCBZ) is approved as adjunctive therapy for partial seizures with and without secondary generalized seizures in adults and as adjunctive therapy for partial seizures in children. OCBZ is a prodrug that is completely metabolized to an active metabolite known as monohydroxycarbamazepine (MHC), which is responsible for OCBZ's therapeutic effect. The elimination half-life is 1 to 2.5 hours for OCBZ and 8 to 10 hours for MHC. The therapeutic range is based on concentrations of the metabolite, not the parent drug; this assay measures the metabolite.

  • Test Type:
  • Pre-test Information:
    Recommended specimen: just before the next dose is due at steady state.
  • Report Delivery:
    Sample by Mon 4 pm; Report Same Day
  • Components:
    0