Troponin I is a specific cardiac marker elevated only in patients suffering from AMI. Troponin T rises 2-4 hours after the onset of myocardial necrosis and remains elevated upto 14 days. It may also be used to monitor patients with non-ischemic causes of cardiac injury. Measurement of both troponins has a sensitivity & specificity of nearly 90% and persistent elevation 12 hours after the onset of chest pain. It has 100% sensitivity in diagnosing AMI. CPK-MB fraction is predominantly found in cardiac muscle.