Molecular Diagnostics

1. What is Molecular Diagnostics?
  • Latest watch word in biological sciences
  • Revolutionized disease diagnosis and prognosis
  • Detecting viruses which are difficult and dangerous to culture like HIV
  • Detecting viruses which are low in number like HIV in antibody negative patients or CMV in transplanted organs
  • May also be used to distinguish antigenically similar viruses like HSV 1& 2
  • Allow to determine antiviral drug susceptibility and to detect infections when viable viruses cannot be obtained
  • Rapid TAT :: Early diagnosis :: Definitive therapy :: Reduction in morbidity & ancillary costs
  • Lending enormous indirect economic benefits
2. PCR tests performed at LPL
a) Infectious Disease Diagnosis: These are classified into below mentioned categories
  • Screening qualitative tests: NTM & MTB, HBV, HCV, HSV 1&2, CMV, HPV PCR
  • Viral load quantitation tests: HIV-1, HBV, HCV, CMV
  • Genotyping test: HCV, HBV (drug resistance)
b) Others: These are classified into below mentioned categories
  • Mutations
  • Venous Thrombosis Risk Analysis/ Factor V Leiden Mutation
  • HLA
  • HLA typing by PCR
  • HLA B27
  • Oncology
  • JAK2
c) Advantages of Real time PCR
Real Time PCR
d) Why should you choose LPL for Molecular Diagnostic testing?
  • First private lab in North India to start molecular diagnostics
  • More than 10 years of experience
  • 1st lab in the country to have PCR lab design as per international guidelines (CLSI and Federal 209E)
  • NABL and CAP accredited