FISH-MYCN AMPLIFICATION

  • Test Usage:
    The MYCN gene, which encodes the n-myc protein, is a proto-oncogene with highest expression in the developing brain and insignificant expression in normal adult tissues. Gene amplification is detected in approximately 20% of Neuroblastoma and a variety of other solid tumors including 5% Medulloblastoma, Glioblastoma multiforme, 25% Alveolar rhabdomyosarcoma, 15-20% Small-cell lung cancer, 40% Neuroendocrine prostate cancer, and 5% Prostate adenocarcinoma. MYCN amplifications are associated with aggressive disease and/or poor outcome. Detection can be useful to stratify patients for aggressive treatment.
  • Report Availability:
    Sample Daily by 4 pm; Report 7 days
  • Sample Report:
10 Diagnostic Centers found for FISH-MYCN AMPLIFICATION in Bijnor